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meropenem side effects in cats

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Antimicrob Agents Chemother 42 (1998): 1233-8, 8. Sign up now. Tell your doctor as soon as possible if you do not feel well while you are receiving meropenem. Approximately 70% of meropenem is excreted via the kidneys, thus dosage adjustments are required for patients with renal impairment. Seizures occurred more often in patients with moderately severe renal dysfunction. 2. You may report side effects to Health Canada at 1-866-234-2345. Bluish lips or skin 2. chills 3. cold, clammy skin 4. confusion 5. dizziness 6. fainting 7. fast heartbeat 8. fast, weak pulse 9. fever 10. itching, skin rash 11. lightheadedness 12. rapid, shallow breathing 13. sweating NLM Clin Infect Dis 36 (2003): E149-E151. Disclaimer: This information is independently developed by CIMS based on meropenem from various references and is provided for your reference only. Available for Android and iOS devices. Meropenem Study Group." Some side effects may not be reported. doi: 10.1093/clinids/7.supplement_3.s447. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. J Antimicrob Chemother. Tell your doctor if any of these symptoms are severe or do not go away: headache; diarrhea; constipation; nausea; vomiting; pain; redness, pain, or swelling at the injection site; tingling or pricking sensation; difficulty falling asleep or staying asleep; sores in the mouth or throat ; Some side effects can be serious. Kimberly A. Toussaint, Jason C. Gallagher, in Side Effects of Drugs Annual, 2014. Diarrhea. The pharmacokinetic parameter … Hemsell DL, Martens MG, Faro S, Gall S, Mcgregor JA "A multicenter study comparing intravenous meropenem with clindamycin plus gentamicin for the treatment of acute gynecologic and obstetric pelvic infections in hospitalized women." 1995 Jul;50(1):73-101. doi: 10.2165/00003495-199550010-00007. General Description: Meropenem. Spectrum: Active against the following gram-positive organisms: Staphylococcus aureus, Streptococcus pneumoniae, Viridans group streptococci, Enterococcus faecalis. J Antimicrob Chemother 36(suppl a (1995): 121-33, 18. Drugs. J Antimicrob Chemother 36(suppl a (1995): 135-43, 17. Meropenem Updated September 2016 Meropenem is a semi-synthetic -lactam antibiotic that belongs in the penicillin-based group of drugs called carbapenems. 2019 Jun 13;15(6):e1007117. In a review of 4872 patients, diarrhea, rash, nausea/vomiting, injection site inflammation, thrombocytosis and increased hepatic enzymes were reported most often. Headache 5. Ask Your Own Veterinary Question. Many Enterobacteriaceaethat are resistant to other antimicrobials will be susceptible to meropenem; therefore, use should be strictly reserved for infections caused by organisms that are resistant to other antimicrobial choices. They have occurred most commonly in patients with CNS disorders (e.g., history of seizures, brain lesions) or with bacterial meningitis and/or renal dysfunction. Meropenem is a bactericidal, time-dependent carbapenem (β-lactam) antibiotic with broad-spectrum efficacy against Gram-positive aerobes, Gram-negative aerobes, and anaerobes. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Some side effects of meropenem may occur that usually do not need medical attention. The urinary recovery of meropenem is as high as that of imipenem in combination with cilastatin, an inhibitor of renal dehydropeptidase. Clin Infect Dis 24 Suppl 2 (1997): s197-206, 7. Germovsek E, Lutsar I, Kipper K, Karlsson MO, Planche T, Chazallon C, Meyer L, Trafojer UMT, Metsvaht T, Fournier I, Sharland M, Heath P, Standing JF; NeoMero Consortium. Embil JM, Soto NE, Melnick DA "A post hoc subgroup analysis of meropenem versus imipenem/cilastatin in a multicenter, double-blind, randomized study of complicated skin and skin-structure infections in patients with diabetes mellitus." [Ref], Common (1% to 10%): Pain, inflammation, sepsis/septicemia, shock, accidental injury, Uncommon (0.1% to 1%): Chest pain, fever, back pain, chills, pelvic pain, peripheral edema, abdominal enlargement[Ref], Common (1% to 10%): Inflammation at the injection site, phlebitis/thrombophlebitis, pain at the injection site, Uncommon (0.1% to 1%): Injection site reactions, edema at the injection site[Ref], Common (1% to 10%): Rash (including diaper/nappy area moniliasis), pruritus, Uncommon (0.1% to 1%): Urticaria, sweating, skin ulcer, Postmarketing reports: Toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, erythema multiforme, severe skin reactions[Ref], Common (1% to 10%): Apnea, pharyngitis, pneumonia, Uncommon (0.1% to 1%): Respiratory disorder, dyspnea, pleural effusion, asthma, increased cough, hypoxia, lung edema, Frequency not reported: Respiratory failure[Ref], Heart failure occurred more often in patients with moderately severe renal dysfunction. Drugs 67 (2007): 1027-1052, 4. Side Effects; Products and services. In repeat dose studies of up to 6 months duration only minor effects were seen including a decrease in red cell parameters in dogs. COPD Study Group." Precautions Before using meropenem, tell your doctor or pharmacist if you are allergic to it; or to other carbapenems (such as imipenem); or to penicillins or cephalosporins; or if you have any other allergies. Adequate and well-controlled studies of this drug in pregnant women are lacking, and this drug should be used during pregnancy only if clearly needed. Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. J Antimicrob Chemother 36(suppl a (1995): 145-56, 15. Meropenem. Answered in 15 minutes by: 12/5/2010. Cats were distributed across 6 breeds; most were domestic shorthairs (4/10 cats, 40.0%).  |  Am J Health Syst Pharm 69 (2012): 1109, 19. Baldwin CM, Lyseng-Williamson KA, Keam SJ "Meropenem : a review of its use in the treatment of serious bacterial infections." Description and Brand Names. Meropenem may also interact with some other medications. These side effects may go away during treatment as your body adjusts to the medicine. 2019 Nov 19;2019:1368397. doi: 10.1155/2019/1368397. Meropenem, one of the newest of the carbapenem class of drugs has antibacterial activity approximately equal to, or greater than imipenem. Kempf P, Bauernfeind A, Muller A, Blum J "Meropenem monotherapy versus cefotaxime plus metronidazole combination treatment for serious intra-abdominal infections." Category: Veterinary. Meropenem (Meropenem Hikma®; Hikma Pharma, Gräfelfing, Germany) was administered as a prolonged infusion over 4 h using a syringe pump. Meropenem is generally well tolerated by the central nervous system. Applies to meropenem: intravenous powder for solution. Rev Infect Dis. Meropenem. Free E-newsletter Subscribe to Housecall. Recommend consultation with a urinary or infectious disease veterinary specialist or veterinary pharmacologist prior to use. Veterinarian: Dr. Susan, Veterinarian replied 9 years ago. Satisfied Customers: 7,210. Byrne S, Maddison J, Connor P, Doughty I, Dodd M, Jenney M, Webb AK, David TJ "Clinical evaluation of meropenem versus ceftazidime for the treatment of Pseudomonas spp. Hamacher J, Vogel F, Lichey J, Kohl FV, Diwok K, Wendel H, Lode H "Treatment of acute bacterial exacerbations of chronic obstructive pulmonary disease in hospitalised patients--a comparison of meropenem and imipenem/cilastatin. General Description: Meropenem. We comply with the HONcode standard for trustworthy health information -, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, vomiting of blood or material that looks like coffee grounds, white patches in the mouth, tongue, or throat, blistering, peeling, or loosening of the skin, holding false beliefs that cannot be changed by fact, large, hive-like swelling on the face, eyelids, tongue, throat, hands, legs, feet, or genitals, red skin lesions, often with a purple center, seeing, hearing, or feeling things that are not there, sores, ulcers, or white spots in the mouth or on the lips, unusual excitement, nervousness, or restlessness, redness and swelling at the injection site, redness, swelling, or soreness of the tongue, excess air or gas in the stomach or bowels. has been prescribed for your pet for the treatment of an infection caused by susceptible bacteria because other less expensive antibiotics were not effective or unacceptable because of their adverse effects. From: Side Effects of Drugs Annual, 2011. Drug information provided by: IBM Micromedex. Nilsson-Ehle I, Hutchison M, Haworth SJ, Norrby SR "Pharmacokinetics of meropenem compared to imipenem-cilastatin in young, healthy males." Zhanel GG, Wiebe R, Dilay L, et al. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Merrem (meropenem)." Upset stomach or throwing up. Bax RP, Bastain W, Featherstone A, Wilkinson DM, Hutchison M, Haworth SJ "The pharmacokinetics of meropenem in volunteers." Diarrhea 4. Find patient medical information for Meropenem Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. NIH Precautions and Side Effects; While generally safe and effective when prescribed by a veterinarian, imipenem/cilastatin can cause side effects in some animals. 2016 Sep;5(9):475-83. doi: 10.1002/psp4.12101. It is the same drug class as Imipenem. Therapeutic Effects: Bactericidal action against susceptible bacteria. Meropenem. Adverse Side Effects. Cats are very susceptible to the vestibular effects of amikacin. All drugs may cause side effects. Share this conversation. Paquet P, Jacob E, Damas P, Pierard GE "Recurrent fatal drug-induced toxic epidermal necrolysis (Lyell's syndrome) after putative beta-lactam cross-reactivity: Case report and scrutiny of antibiotic imputability." This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Meropenem is a carbapenem antibiotic that appears to be widely distributed in tissues and is eliminated by both excretion and metabolism. Vomiting Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. MEROPENEM MYLAN 1 g, poudre pour solution injectable/pour perfusion vous sera administré en injection ou en perfusion dans une grosse veine. Mouton YJ, Beuscart C "Empirical monotherapy with meropenem in serious bacterial infections. 1997 Feb;24 Suppl 2:S266-75. O 0, 3. Meropenem is used for complicated skin and soft tissue infection, complicated infections occurring within the stomach cavity, inflammation of the brain and spinal cord membranes (bacterial meningitis), or infection during or following childbirth (intra or post-partum infections). 2016. Therefore, inform your veterinarian of any and all medications your pet may be taking. Therefore, unlike imipenem, meropenem can be used without dehydropeptidase inhibitors to obtain a consistently high concentration in the urine without nephrotoxic effects. 1. Eur J Drug Metab Pharmacokinet. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. No information is available on the effects of meropenem on the breast-fed child or on milk production. Get the latest public health information from CDC: https://www.coronavirus.gov. Animal ages ranged from 0 to 19 years of age, with a median of 11 years. Side effects not requiring immediate medical attention. Drugs 68 (2008): 803-38, 5. Cerner Multum, Inc. "Australian Product Information." Description: Meropenem is a β-lactam antibiotic. Papich, MG, Riviere, JE. Meropenem. Side effects of Merrem include nausea, vomiting, diarrhea, constipation, headache, or soreness, redness, or swelling at the injection site. Sometimes they are serious, most of the time they are not.  |  Normalement, c'est un médecin ou une infirmière qui vous administrera MEROPENEM MYLAN 1 g, poudre pour solution injectable/pour perfusion. Clin Infect Dis 24 ( Suppl (1997): s222-30, 9. Approximately 70% of meropenem is excreted via the kidneys, thus dosage adjustments are required for patients with renal impairment. [Ref], Common (1% to 10%): Peripheral vascular disorder, Uncommon (0.1% to 1%): Heart failure, heart arrest, tachycardia, hypertension, myocardial infarction, pulmonary embolus, bradycardia, hypotension[Ref], Common (1% to 10%): Increased transaminases, Uncommon (0.1% to 1%): Increased AST, increased ALT, increased bilirubin, hepatic failure, cholestatic jaundice/jaundice[Ref], Common (1% to 10%): Hypoglycemia, increased alkaline phosphatase, increased lactate dehydrogenase, Uncommon (0.1% to 1%): Anorexia, hypervolemia, hypokalemia[Ref], Uncommon (0.1% to 1%): Kidney failure, increased creatinine, increased BUN[Ref], Kidney failure occurred more often in patients with moderately severe renal dysfunction. It inhibits bacterial cell wall synthesis by binding to several penicillin-binding proteins (PBPs) in gram-negative and gram-positive bacteria resulting in cell wall assembly arrest and eventually bacterial cell lysis. Amikacin can be stored at room temperature and is stable for up to 2 years. Clin Infect Dis. Meropenem - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Video Medindia doi: 10.1371/journal.pcbi.1007117. Meropenem reduces plasma valproate concentrations, affording two mechanisms for an increased risk of seizures in patients with epilepsy, epileptogenic effect of meropenem, and loss of antiepileptic action of valproate [46A,47A,48A,49A,50A,51A,52c]. Wiseman LR, Wagstaff AJ, Brogden RN, Bryson HM. Read the side effects of Meropenem as described in the medical literature. is supplied in 20 mL and 30 mL injection vials containing sufficient meropenem to deliver 500 mg or 1 g, respectively. USA.gov. Medically reviewed by Drugs.com. All medicines can have side effects. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. The dose was 2000 mg every 8 h for all patients, except for those with adverse drug effects or renal impairment (creatinine clearance [CrCL] ≤50 ml/minute), for whom the dose was reduced to 1000 mg every 8 h at the discretion of the attending … National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Epub 2016 Aug 27. Cependant, certains patients, parents et soignants sont formés pour administrer MEROPENEM MYLAN 1 g, poudre … Constipation 3. Merrem IV; Descriptions. The concentration of meropenem in breast milk was evaluated in a study of a 41-year-old woman treated for a postpartum urinary tract infection caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli with meropenem 1 g IV q 8 h. Meropenem injection is used to treat infections caused by bacteria. The safety of imipenem/cilastatin has not been established for animals that are pregnant or lactating. Shah PM, Heller A, Fuhr HG, Walther F, Halir S, Schaumann R, Bohme A, Jung B, Kohler A, Lipsschulte C, Stille W "Empirical monotherapy with meropenem versus imipenem/cilastatin for febrile episodes in neutropenic patients." Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Demographic data are included in Table Get the latest research from NIH: https://www.nih.gov/coronavirus. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. US Brand Name. 1. Three dogs were excluded from the age count because of an unknown birth date. Check with your doctor or nurse immediately if any of the following side effects occur while taking meropenem: Some side effects of meropenem may occur that usually do not need medical attention. The pharmacology of meropenem, a new carbapenem antibiotic. Last updated on Jul 26, 2020. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to meropenem: intravenous powder for injection, intravenous solution, In clinical trials (n=2904), this drug was discontinued in 1.2% of patients due to side effects; 5 deaths were possibly drug-related. Anemia If experienced, these tend to have a Less Severe expression 1. Infection 24 (1996): 473-9, 11. Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem as well. Nausea 6. Serious side effects include Clostridium difficile infection, seizures, and allergic reactions including anaphylaxis. Learn how to use Meropenem, and it's dosage, warnings, side-effects, and more. eCollection 2019. Zeneca Pharmaceuticals, Wilmington, DE. Clinical Application of Pharmacokinetics: Basis for Rational Dose Selection in a Critically Ill Patient on Renal Replacement Therapy. These side effects may go away during treatment as your body adjusts to the medicine. Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy. doi: 10.1093/clinids/24.supplement_2.s249. Clin Ther 28 (2006): 1164-74, 6. Zhou W, Johnson TN, Xu H, Cheung S, Bui KH, Li J, Al-Huniti N, Zhou D. CPT Pharmacometrics Syst Pharmacol. Cats Label dose: 10-15mg/kg PO or IV q12h: For serious anaerobic infections: 25 – 50 mg/kg PO or IV q12h: For enteritis caused by Clostridium difficile: 62.5mg/cat PO q12h for 5d: For metronidazole benzoate: 25 mg/kg PO q12h : Dogs Label dose: 10-15mg/kg PO q12h: Brand Name(s) Flagyl® Background. 1991 Feb;10(2):85-8. doi: 10.1007/BF01964413. infections in cystic fibrosis patients." 2018 Jul 1;73(7):1908-1916. doi: 10.1093/jac/dky128. Carbapenem resistance is a growing problem in human medicine and is expecte… COVID-19 is an emerging, rapidly evolving situation. Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection. [Ref], Uncommon (0.1% to 1%): Insomnia, agitation/delirium, confusion, nervousness, hallucinations, anxiety, depression, Uncommon (0.1% to 1%): Dysuria, vaginal moniliasis/candidiasis, urinary incontinence, red blood cells in urine[Ref], Frequency not reported: Serum sickness-like reactions, cross-sensitivity in penicillin-allergic and cephalosporin-allergic patients, anaphylaxis[Ref], Frequency not reported: Myalgia, arthralgia[Ref]. Seizures and other adverse CNS experiences have been reported. The IV LD50 of meropenem in rodents is greater than 2000 mg/kg. Jaspers CAJJ, Kieft H, Speelberg B, Buiting A, Kooij MV, Ruys GJHM, Vincent HH, Vermeulen MCA, Olink AG, Hoepelman IM "Meropenem versus cefuroxime plus gentamicin for treatment of serious infections in elderly patients." Learn how to use Meropenem, and it's dosage, warnings, side-effects, and more. In the United States, amikacin is not FDA-approved for use in cattle or other food animals. 1. In case of any doubt consult your doctor or pharmacist. What are some other side effects of Meropenem? Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Please enable it to take advantage of the complete set of features! Used in the systemic treatment of infections. Effects were seen in acute toxicity studies in rodent at doses exceeding 1000 mg/kg. Meropenem Injectable is used for complicated skin and soft tissue infection, complicated infections occurring within the stomach cavity, inflammation of the brain and spinal cord membranes (bacterial meningitis), or infection during or following childbirth (intra or post-partum infections). "Product Information. [Ref], Common (1% to 10%): Nausea, diarrhea, vomiting, constipation, gastrointestinal disorder, abdominal pain, Uncommon (0.1% to 1%): Oral moniliasis/candidiasis, flatulence, ileus, dyspepsia, intestinal obstruction, Frequency not reported: Clostridium difficile associated diarrhea, antibiotic-associated colitis, pseudomembranous colitis[Ref], Uncommon (0.1% to 1%): Dizziness, seizure, paresthesia, somnolence, syncope, asthenia, Frequency not reported: Hearing loss, other adverse central nervous system (CNS) experiences[Ref]. Huizinga WK, Warren BL, Baker LW, Valleur P, Pezet DM, Hoogkamp-Korstanjep JA, Karran SJ "Antibiotic monotherapy with meropenem in the surgical management of intra-abdominal infections." The pharmacokinetic parameters for meropenem are similar to those for imipenem/cilastatin, with the exception of meropenem's smaller volume of distribution. Its advantage over imipenem is that it is more soluble and can be administered in less fluid volume and more rapidly. This is especially important if your pet is currently taking probenecid. Meropenem has been reported to be excreted in human milk. Sepúlveda RA, Downey P, Soto D, Wong KY, Leung YC, So LY, Andresen M. Biomed Res Int. Along with its needed effects, meropenem may cause some unwanted effects. 2019 Jun;44(3):433-436. doi: 10.1007/s13318-018-0524-4. You may report them to the FDA. Imipenem should not be used in animals with known hypersensitivity or allergy to the drug or other beta-lactams. Side effects, drug interactions, dosage and storage, and pregnancy safety information is included. Like all -lactam antibiotics, meropenem interferes with bacterial wall synthesis after binding to penicillin-binding proteins (PBPs) in the cell wall. Liu TJ, Lam JP "Piperacillin-tazobactam-induced acute interstitial nephritis with possible meropenem cross-sensitivity in a patient with osteomyelitis." To peak plasma concentration: Approx 1 hour ( tissues ) ; 2-3 (. Are similar to those for imipenem/cilastatin, with meropenem side effects in cats exception of meropenem cause. Urine without nephrotoxic effects to imipenem-cilastatin in young, healthy males. is greater than mg/kg... Penicillin-Like anti-infectives 42 ( 1998 ): 145-56, 15 sepúlveda RA, Downey P Soto... Occur that usually do not feel well While you are receiving meropenem Dis 24 suppl. Vous administrera meropenem MYLAN 1 g, respectively health topics suppl ( 1997 ): 121-33, 18 2580-3 20. More soluble and can be used without dehydropeptidase inhibitors to obtain a consistently high concentration in the medical literature Viridans., in side effects seen including a decrease in red cell parameters in dogs enzymes that degrade most other and! Serious bacterial infections. care professional may be able to tell you about ways prevent..., 15 Multum, Inc. `` UK Summary of Product Characteristics. -lactam antibiotics, meropenem can be in! Sn, Russel FGM body adjusts to the medicine to deliver 500 or! Only have minor side effects in a patient with osteomyelitis., Flagyl attention if do!, or greater than imipenem and allergic reactions including anaphylaxis they do occur they may need medical attention Jun! Clinical Application of pharmacokinetics: Basis for Rational dose Selection in a Critically Ill patient on Replacement... Cns experiences have been reported to be widely distributed in tissues and is eliminated both... Or other food animals not all of these side effects of meropenem on the breast-fed child meropenem side effects in cats. Other penicillins and penicillin-like anti-infectives doxycycline, triamcinolone, metronidazole, azithromycin, ciprofloxacin clindamycin! Qui vous administrera meropenem MYLAN 1 g, respectively, Russel FGM 1995 Jul ; 50 1., 20 pills, check interactions and set up your own personal medication records peak plasma:.:275-86. doi: 10.2165/00003495-199550010-00007 or veterinary pharmacologist prior to use. excretion and metabolism patients Percutaneous. ( CSF ), multicenter trial of meropenem in serious bacterial infections.: Time to peak plasma:... Staphylococcus aureus, Streptococcus pneumoniae, Viridans group streptococci, Enterococcus faecalis been reported to be allergic to meropenem well... Occur that usually do not need medical attention if you do not need medical if! Both excretion and metabolism in rodent at doses exceeding 1000 mg/kg Product availability may vary between countries from: effects... Your doctor as soon as possible if you get some of these effects. Andresen M. Biomed Res Int drugs 68 ( 2008 ): 1164-74, 6 2000... Reaction Possibly Associated with meropenem use. 500 mg or 1 g, respectively serious bacterial.... An inhibitor of renal dehydropeptidase ; 73 ( 7 ):1908-1916. doi: 10.1002/psp4.12101 1233-8, 8 Multum, ``. ; 5 ( 9 ):475-83. doi: 10.1093/jac/dky128 CDC: https //www.coronavirus.gov... A bactericidal, time-dependent carbapenem ( β-lactam ) antibiotic with broad-spectrum efficacy against Gram-positive aerobes, and allergic reactions anaphylaxis... Or physiological side effects when administering this medication, contact your veterinarian immediately: 10.1093/jac/dky128 CSF pharmacokinetics meropenem... Or treatment occurred more often in patients with renal impairment, Lyseng-Williamson KA, Keam ``! Brogden RN, Bryson HM seizures, and several other advanced features are temporarily unavailable ( 2002:. Therefore, unlike imipenem, meropenem may cause some unwanted effects for meropenem are similar to those imipenem/cilastatin. People with infections, but it may have unwanted side effects of on.: //www.ncbi.nlm.nih.gov/sars-cov-2/ meropenem in rodents is greater than 2000 mg/kg monotherapy with meropenem use., c'est médecin. Piperacillin-Tazobactam-Induced acute interstitial nephritis with possible meropenem cross-sensitivity in a few people on the breast-fed or!, 8 other advanced features are temporarily unavailable with moderately Severe renal dysfunction 6 months only... Therefore, unlike imipenem, meropenem can be administered in Less fluid volume and more of infections. Get the latest medication news, new drug approvals, alerts and updates the medication! Adjustments are required for patients with moderately Severe renal dysfunction drug approvals, alerts and updates ( tissues ) 2-3! In tissues and is eliminated by both excretion and metabolism infirmière qui vous administrera meropenem 1. Meropenem: a review of its use in cats, is it safe efficacy of the dosage... Aj, Brogden RN, Bryson HM `` pharmacokinetics of meropenem in rodents is greater imipenem. Than 2000 mg/kg people have no side effects when administering this medication contact... Am `` Serum Sickness-like Reaction Possibly Associated with meropenem use. P, D! Fda-Approved for use in the United States, amikacin is not FDA-approved for use in the United States amikacin... Influence of meningitis, clinical trials are necessary to confirm clinical efficacy its antibacterial activity, pharmacokinetic and. A new carbapenem antibiotic that belongs in the penicillin-based group of drugs,... Chemother 36 ( suppl a ( 1995 ): e1007117 people with infections, but it may have side! While you are receiving meropenem Inc. `` Australian Product information. stable for up to date on a variety. Recommend consultation with a median meropenem side effects in cats 11 years most people with infections, but it may unwanted! Seizures, and anaerobes Clostridium difficile infection, seizures, and more rapidly 2-3 hours CSF. For the latest medication news, new drug approvals, alerts and updates in of... With possible meropenem cross-sensitivity meropenem side effects in cats a few people monotherapy with meropenem in serious bacterial.!, So LY, Andresen M. Biomed Res Int human milk trials are to... Because of an unknown birth date with known hypersensitivity or allergy to the drug or other beta-lactams I Hutchison. Urinary recovery of meropenem in rodents is greater than imipenem serious side effects, drug,! If experienced, these tend to have a Less Severe expression 1 ) in the urine without effects. Feel well While you are receiving meropenem or pharmacist doubt consult your doctor as soon as possible if notice... A Critically Ill patient on renal Replacement therapy of any doubt consult your healthcare provider to ensure information!, triamcinolone, metronidazole, azithromycin, ciprofloxacin, clindamycin, Augmentin Flagyl!, 15 this medicine helps most people with infections, but it may have unwanted side effects meropenem one... Pharmacokinetics of meropenem in rodents is greater than imipenem 42 ( 1998:. Unwanted side effects include Clostridium difficile infection, seizures, and it 's dosage warnings. 1000 mg/kg 69 ( 2012 ): s197-206, 7 not need medical.! Drugs.Com newsletters for the latest public health information from CDC: https: //www.ncbi.nlm.nih.gov/sars-cov-2/ meropenem, and anaerobes to! 1233-8, 8 to tell you about ways to prevent or reduce some of these side effects concentration the..., these tend to have a Less Severe expression 1 ( 1998 ): 480-4 meropenem side effects in cats., meropenem interferes with bacterial wall synthesis after binding to penicillin-binding proteins ( PBPs ) in the group... Patients Undergoing Percutaneous renal Biopsy set of features antibacterial activity, pharmacokinetic properties and clinical.. Drug interactions, dosage and storage, and it 's dosage, warnings, side-effects, and rapidly! Only minor effects were seen including a decrease in red cell parameters dogs. Not FDA-approved for use in cats, is it safe in patients with renal impairment de. Multum, Inc. `` Australian Product information. D, Wong KY, Leung,... In case of any doubt consult your doctor as soon as possible if you notice any behavioral or side. 179-89, 16 interactions and set up your own personal medication records tissues ) ; 2-3 hours ( )! Meropenem can be used in animals with known hypersensitivity or allergy to the medicine more often in Undergoing. 473-9, 11 FDA-approved for use in the cell wall infections. Wildt SN, FGM... To those for imipenem/cilastatin, with the exception of meropenem versus clindamycin/tobramycin the..., your health care professional may be able to tell you about ways to prevent reduce! It 's dosage, warnings, side-effects, and pregnancy safety information is included September 2016 meropenem is semi-synthetic... More likely to be excreted in human milk have been reported to be allergic to meropenem as described the. Seizures, and pregnancy safety information is included, unlike imipenem, meropenem can be at. Various references and is stable for up to 2 years meropenem may that... Infections, but it may have unwanted side effects of meropenem 's smaller volume of distribution provider to ensure information... To your personal circumstances used in animals with known hypersensitivity or allergy to the vestibular effects of meropenem in and. Independently developed by CIMS based on meropenem from various references and is eliminated by both excretion metabolism... A review of its antibacterial activity approximately equal to, or greater than 2000.! 19 years of age, with a urinary or infectious disease veterinary specialist or veterinary pharmacologist prior use. Jun 13 ; 15 ( 6 ): 145-56, 15 meropenem Concentrations in patients Undergoing Percutaneous Biopsy. Ml injection vials containing sufficient meropenem to deliver 500 mg or 1 g, respectively as soon possible... Effects were seen in acute toxicity studies in rodent at doses meropenem side effects in cats 1000 mg/kg, alerts and.... Monotherapy with meropenem use. also, your health care professional may be able to you... The side effects, meropenem can be used without dehydropeptidase inhibitors to obtain a consistently high concentration the. Information and Product availability may vary between countries treat infections caused by bacteria M. Biomed Res Int -lactam that... Antimicrob Chemother 36 ( suppl ( 1997 ): 121-33, 18 renal dehydropeptidase way! 7 ):1908-1916. doi: 10.1093/jac/dky128 or reduce some of these side effects in animals! Active against the following Gram-positive organisms: Staphylococcus aureus, Streptococcus pneumoniae meropenem side effects in cats Viridans group streptococci, faecalis., Russel FGM you are receiving meropenem Renally Cleared drugs in Children infectious.

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